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Updated: Mar 14, 2026

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Airway observations during upper endoscopy predicting obstructive sleep apnea.

Glenn Harvin1, Eslam Ali1, Amit Raina1

  • 1Department of Gastroenterology Brody School of Medicine at East Carolina University (Glenn Harvin, Eslam Ali, Amit Raina, William Leland), USA.

Annals of Gastroenterology
|October 7, 2016
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Summary

Upper endoscopy can identify airway collapse, a key indicator for obstructive sleep apnea risk. This pilot study suggests its potential as a diagnostic tool for sleep disordered breathing.

Keywords:
Berlin questionnaireUpper endoscopyairwaysleep apnea

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Area of Science:

  • Otolaryngology
  • Sleep Medicine
  • Gastroenterology

Background:

  • Obstructive sleep apnea (OSA) is a common condition associated with significant health risks.
  • Identifying individuals at high risk for OSA is crucial for timely intervention.
  • Current diagnostic methods can be invasive or require specialized equipment.

Purpose of the Study:

  • To investigate the utility of upper endoscopy in assessing airway characteristics.
  • To determine if specific airway collapse patterns during endoscopy correlate with high OSA risk.
  • To explore upper endoscopy as a potential screening tool for sleep disordered breathing.

Main Methods:

  • A pilot study involving patients undergoing routine upper endoscopy.
  • Patients were stratified into high and low risk groups for sleep disordered breathing using the Berlin Questionnaire.
  • Airway collapse was evaluated at multiple levels (palate/uvula/tonsils, tongue base, hypopharynx, larynx) and scored for severity.

Main Results:

  • Patients with partial or complete airway obstruction during endoscopy were more likely to have a positive Berlin Questionnaire.
  • Higher total airway collapse scores were observed in patients with a positive Berlin Questionnaire.
  • Patients at high risk for OSA tended to have increased weight, BMI, and neck circumference.

Conclusions:

  • Upper endoscopy reveals airway collapse patterns that may indicate a higher risk for obstructive sleep apnea.
  • These preliminary findings suggest upper endoscopy could be a valuable tool in evaluating patients for OSA.
  • Further research is warranted to validate the role of upper endoscopy in OSA diagnosis.