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Predictors of hospital re-admissions among Hispanics with hepatitis C-related cirrhosis

Pradeep R Atla1, Muhammad Y Sheikh1, Firdose Gill2

  • 1Division of Gastroenterology, Hepatology and Nutrition, University of California San Francisco, Fresno MEP (Pradeep R. Atla, Muhammad Y. Sheikh, Rabindra Kundu, Jayanta Choudhury), Fresno, California, USA.

Annals of Gastroenterology
|October 7, 2016
PubMed

Insights

Hospital readmissions for decompensated cirrhosis are common, especially among Hispanics with hepatitis C virus (HCV)-related cirrhosis. Alcohol use, hepatic encephalopathy (HE), varices, and advanced Child-Turcotte-Pugh (CTP) class predict readmissions in this population.

Area of Science:

  • Hepatology
  • Gastroenterology
  • Public Health

Background:

  • Hospital readmissions in decompensated cirrhosis worsen patient outcomes.
  • Hispanics face a high burden of hepatitis C virus (HCV)-related liver disease.
  • Understanding readmission factors in this demographic is crucial for improving care.

Purpose of the Study:

  • To identify factors contributing to hospital readmission rates.
  • To focus on Hispanic patients with HCV-related cirrhosis.
  • To inform targeted interventions for reducing readmissions.

Main Methods:

  • Retrospective review of 292 HCV-related cirrhosis admissions (2009-2012).
  • Compared Hispanic (n=189) and non-Hispanic (n=103) patient data.
  • Used logistic regression to determine predictors of hospital readmissions.

Main Results:

  • Hispanics constituted 71% of the 132 cirrhosis-related readmissions.
  • Hepatic encephalopathy (HE) and variceal hemorrhage were primary readmission causes.
  • Predictors for readmission in Hispanics included alcohol use, HE, varices, and advanced Child-Turcotte-Pugh (CTP) class.

Conclusions:

  • Advanced CTP class (B and C) is a major predictor of readmission in Hispanics with HCV-related cirrhosis.
  • HE and variceal hemorrhage are the main drivers of these readmissions.
  • Identifying these factors can guide strategies to reduce hospital readmissions.
Abstract

Keywords:
Child-Turcotte-Pugh classhepatic encephalopathynon-Hispanicsprophylactic β-blockersvariceal hemorrhage

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