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New platelet indices as inflammatory parameters for patients with rheumatoid arthritis
Metin Işık1, Hatice Şahin2, Engin Hüseyin2
1Department of Rheumatology, Bülent Ecevit University Faculty of Medicine, Zonguldak, Turkey.
Objective:
To test new platelet indices for patients with rheumatoid arthritis (RA) as new acute phase reactants.
Material And Methods:
In total, 120 patients with RA and 40 patients in the control group were analyzed. A DAS 28 score over 2.6 was accepted as active disease, and a DAS 28 score lower than 2.6 was accepted as under remission. Platelet distribution width, plateletcrit, and mean platelet volume were analyzed for three groups: patients with active RA, patients under remission, and the control group.
Results:
There were 72 patients with active disease and 48 patients under remission. The erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), mean platelet volume (MPV), plateletcrit (PTC), and platelet distribution width (PDW) scores were all statistically different among groups. In our data, PTC was found to be a positive acute phase reactant and others were negative acute phase reactants for patients with RA.
Conclusion:
These new indices are cheap, widely available, and useful parameters for routine clinical rheumatology practice.
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