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Immunotropic Properties of Immobilized Interferon-α2b

E Yu Sherstoboev1, O G Shitikova2, N V Masnaya2

  • 1E. D. Goldberg Research Institute of Pharmacology and Regenerativ Medicine, Tomsk, Russia. sherstoboev_eu@pharmso.ru.

Bulletin of Experimental Biology and Medicine
|October 7, 2016
PubMed

Course treatment with IFN-α2b immobilized on polyethylene glycol stimulates phagocytic activity of peritoneal macrophages and neutrophils, enhances humoral immune response in CBA/CaLac mice, stimulates IL-4 synthesis, and suppresses IFN-γ production by mitogenstimulated splenocytes from experimental animals.

Keywords:
cytokinesinterferon-α2bpegylationphagocytosis

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