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Microsecond and nanosecond polyproline II helix formation in aqueous nanodrops measured by mass spectrometry
Daniel N Mortensen1, Evan R Williams1
1Department of Chemistry, University of California, Berkeley, California 94720-1460, USA. erw@berkeley.edu.
Chemical Communications (Cambridge, England)
|October 7, 2016
Abstract:
The 1.5 μs and <400 ns time constants for the formation of polyproline II helix structures in 21 and 16 residue peptides, respectively, are measured using rapid mixing from theta-glass emitters coupled with mass spectrometry. Results from these studies should serve as useful benchmarks for comparison with computational simulation results.
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