Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Complexation Equilibria: Factors Influencing Stability of Complexes01:09

Complexation Equilibria: Factors Influencing Stability of Complexes

922
In complexation reactions, metal cations are the electron pair acceptors, and the ligands are the electron pair donors. The stability of the metal complexes depends primarily on the complexing ability of the central metal ion and the nature of the ligands. Generally, the complexing ability of the metal ion depends on the size and charge of the ion. As the metal ion size increases, the stability of the metal complexes decreases, provided that the valency of the metal ion and the ligands remain...
922
Ionic Crystal Structures02:42

Ionic Crystal Structures

19.8K
Ionic crystals consist of two or more different kinds of ions that usually have different sizes. The packing of these ions into a crystal structure is more complex than the packing of metal atoms that are the same size.
Most monatomic ions behave as charged spheres, and their attraction for ions of opposite charge is the same in every direction. Consequently, stable structures for ionic compounds result (1) when ions of one charge are surrounded by as many ions as possible of the opposite...
19.8K
Molecular Structure and Acidity02:34

Molecular Structure and Acidity

22.2K
An acid can be deprotonated to form a conjugate base or an anion. If the produced anion is more stable, then the acid is stronger. On the contrary, if the anion is unstable, then the acid is weaker. Hence, to determine the acidity of the compound, the stability of its conjugate base is studied using various factors.
The size effect explains the change in atomic size on acidity. When comparing the acids formed from elements that belong to the same column in the periodic table, their atomic sizes...
22.2K
Complexation Equilibria: The Chelate Effect01:19

Complexation Equilibria: The Chelate Effect

1.5K
In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...
1.5K
Metal-Ligand Bonds02:51

Metal-Ligand Bonds

25.3K
The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
25.3K
Ions as Acids and Bases02:54

Ions as Acids and Bases

27.2K
Salts with Acidic Ions
Salts are ionic compounds composed of cations and anions, either of which may be capable of undergoing an acid or base ionization reaction with water. Aqueous salt solutions, therefore, may be acidic, basic, or neutral, depending on the relative acid-base strengths of the salt’s constituent ions. For example, dissolving the ammonium chloride in water results in its dissociation, as described by the equation:
27.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transient and Regulated Cycles of Chemically Driven Disassembly and Reassembly in Anion-Driven Supramolecular Polymers.

Journal of the American Chemical Society·2026
Same author

Physics-informed machine learning model for accurate prediction of electron affinities.

The Journal of chemical physics·2026
Same author

Ladderanes: Stepping Up as Nonclassical <i>ortho</i>-Substituted Benzene Bioisosteres.

Journal of the American Chemical Society·2026
Same author

MIM-ML: Combining Molecular Fragmentation and Machine Learning for Accurate Prediction of NMR Chemical Shifts for Large Peptides.

The journal of physical chemistry. A·2026
Same author

Hydrogen Isotope Exchange in Pyridine Catalyzed by an Iron(II) Imido Complex: Counterion-Directed Regioselectivity.

Angewandte Chemie (International ed. in English)·2026
Same author

Cyaphido Complexes of the Rare-Earth Metals and Their Tetramerization.

Journal of the American Chemical Society·2026

Related Experiment Video

Updated: Mar 14, 2026

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
11:04

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

Published on: September 7, 2019

9.9K

Anions Stabilize Each Other inside Macrocyclic Hosts.

Elisabeth M Fatila1, Eric B Twum1, Arkajyoti Sengupta1

  • 1Dept. of Chemistry, Indiana University Bloomington, 800 E. Kirkwood Ave., Bloomington, IN, 47405, USA.

Angewandte Chemie (International Ed. in English)
|October 7, 2016
PubMed
Summary
This summary is machine-generated.

Researchers demonstrate that bisulfate anions can form stable dimers, stabilized by hydrogen bonds within macrocycles. This finding provides experimental evidence for anion dimerization, challenging simple electrostatic predictions.

Keywords:
anion recognitionbisulfateshydrogen bondingmacrocyclessupramolecular chemistry

More Related Videos

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry
07:33

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry

Published on: October 15, 2018

15.1K
Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group
07:49

Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group

Published on: August 16, 2017

7.5K

Related Experiment Videos

Last Updated: Mar 14, 2026

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
11:04

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

Published on: September 7, 2019

9.9K
Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry
07:33

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry

Published on: October 15, 2018

15.1K
Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group
07:49

Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group

Published on: August 16, 2017

7.5K

Area of Science:

  • Supramolecular Chemistry
  • Physical Chemistry
  • Chemical Physics

Background:

  • Coulomb's law suggests anions repel, yet theoretical models propose anion dimerization.
  • Experimental evidence for metastable anion dimers and their mutual stabilization is lacking.

Purpose of the Study:

  • To provide experimental evidence for anion dimerization.
  • To investigate the stabilization mechanism of anion dimers.
  • To characterize the properties of bisulfate anion dimers.

Main Methods:

  • Encapsulation of bisulfate anions within cyanostar macrocycles.
  • Spectroscopic analysis including 1H NMR.
  • Observation of the dimer across different states of matter.

Main Results:

  • Formation of a stable 2:2 complex of bisulfate homodimers.
  • Stabilization through self-complementary hydrogen bonds (OH···O).
  • Observation of a 1H NMR peak at 13.75 ppm, indicative of borderline-strong hydrogen bonds.

Conclusions:

  • Bisulfate anions can form metastable dimers stabilized by hydrogen bonds.
  • Anion dimerization is experimentally confirmed, contrary to simple electrostatic expectations.
  • The observed bisulfate dimer is stable in solution and other states of matter.