Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Retinal adaptation effects on the patterned VEP and ERG.

M M Spafford1, S L Lu

  • 1School of Optometry, University of Waterloo, Ontario, Canada.

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|August 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterizing α-phase variants in titanium alloys via EBSD: Understanding colour indexing challenges.

Micron (Oxford, England : 1993)·2025
Same author

[Clinical effects of pedicled omental flap transplantation in repairing secondary rejection wounds after brain pacemaker implantation].

Zhonghua shao shang yu chuang mian xiu fu za zhi·2023
Same author

[Application value of flexible endoscopy and rigid endoscopy in the clinical examination of chronic sinus tract wounds with different shapes].

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns·2021
Same author

[To master the rules and characteristics of wound repair for wound healing promotion].

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns·2021
Same author

[Receptor pathways of glycated basic fibroblast growth factor affecting the proliferation and vascularization of human dermal microvascular endothelial cells].

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns·2021
Same author

[Some thoughts on the coordinated development of burn department and wound repair department].

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns·2020

Retinal adaptation significantly influences visual potentials, with dark adaptation yielding larger amplitudes for patterned visually evoked potentials (pVEP) and patterned electroretinograms (pERG) at larger field sizes. Field size is crucial for observing adaptation effects.

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Visual Science

Background:

  • The patterned visually evoked potential (pVEP) and patterned electroretinogram (pERG) are electrophysiological measures used to assess visual pathway function.
  • Retinal adaptation, the process by which the eye adjusts to different light levels, can influence these responses.

Purpose of the Study:

  • To investigate the effects of light and dark adaptation on pVEP and pERG in visually normal observers.
  • To determine the influence of stimulus field size on retinal adaptation effects in pVEP and pERG.

Main Methods:

  • 10 visually normal human observers participated in the study.
  • pVEP and pERG were recorded under light and dark adaptation conditions.
  • Stimulus field sizes of 6 and 12 degrees were utilized.

Related Experiment Videos

Main Results:

  • Retinal adaptation effects on pVEP were field-size dependent.
  • At a 12-degree field size, dark-adapted steady-state pVEP (ssVEP) and transient pVEP (tVEP) amplitudes were significantly larger than light-adapted amplitudes.
  • Similarly, pERGs elicited by a 12-degree field showed larger amplitudes in dark-adapted conditions compared to light-adapted conditions.
  • No significant adaptation effects were observed with a 6-degree field size.

Conclusions:

  • Retinal preadaptation significantly impacts pVEP and pERG amplitudes, particularly at larger stimulus field sizes.
  • Dark adaptation enhances pVEP and pERG responses more than light adaptation when using a 12-degree field.
  • Monitoring temporal changes in pVEP for adaptation levels was inconclusive under the studied conditions.