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Updated: Mar 14, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia
Patricia M Fortin1, Karen V Madgwick2, Marialena Trivella3
1Systematic Review Initiative, NHS Blood and Transplant, Oxford, UK.
Abstract:
This is the protocol for a review and there is no abstract. The objectives are as follows: To identify and assess the effectiveness of interventions to improve adherence to iron chelation therapy compared to standard care in people with SCD or thalassaemia including: identifying and assessing the effectiveness of different types of interventions (psychological and psychosocial, educational, medication interventions, or multi-component interventions);identifying and assessing the effectiveness of interventions specific to different age groups (children, adolescents, adults).
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