Related Experiment Videos
[Continuous respiratory therapy of newborn and premature infants with respiratory disorders]
Insights
Respiratory therapy is more effective for newborns with pulmonary diseases, showing a 59.3% survival rate compared to 16.9% for extrapulmonary causes. Early intervention in hospital-born infants reduced mortality and complications.
Area of Science:
- Neonatal medicine
- Pediatric respiratory care
- Critical care neonatology
Context:
- Long-term respiratory therapy was administered to 2216 neonates and premature infants experiencing respiratory distress between 1975 and 1985.
- 81.2% of the patient cohort were premature infants.
- Patients were categorized into two groups: 1813 with pulmonary diseases and 403 with extrapulmonary conditions.
Purpose:
- To evaluate the efficacy of respiratory therapy in newborns with diverse respiratory distress causes.
- To compare survival rates and complication frequencies between pulmonary and extrapulmonary etiologies.
- To analyze the impact of inborn versus transported status on outcomes.
Summary:
- Respiratory therapy was applied to 1813 neonates for pulmonary issues (e.g., hyaline membrane disease, pneumonia, meconium aspiration) and 403 for extrapulmonary causes (primarily neurological).
- Survival rates were significantly higher for the pulmonary group (59.3%) than the extrapulmonary group (16.9%).
- Inborn infants receiving early respiratory therapy exhibited lower mortality and complication rates.
Impact:
- Respiratory therapy demonstrates greater effectiveness in treating neonatal respiratory distress stemming from pulmonary conditions.
- Early respiratory support for hospital-born neonates is crucial for improving survival and minimizing severe complications.
- Findings underscore the importance of timely diagnosis and intervention in neonatal respiratory distress management.
Abstract:
2216 newborns and prematures with respiratory distress of different underlying diseases were treated with long term respiratory therapy from 1. Jan. 1975 to 31. Dec. 1985. One part of the patients were born in our hospital, the other part of them were transported from outside. The rate of prematures was 81.2%. The respiratory therapy was applied in 1813 cases because of pulmonary diseases (group 1.), while in 403 cases the respiratory troubles were extrapulmonary in origin (group 2.). The diseases in the first group were as follows: hyaline membrane disease in 482 cases (27.30%), intrauterine pneumonia in 634 cases (34.64%), postnatal pneumonia in 291 cases (15.90%), meconium aspiration syndrome in 110 cases (6.01%), severe RDS-II in 158 cases (8.63%), pulmonary immaturity in 116 cases (6.35%), persistent fetal circulation in 21 cases (1.15%) and pulmonary aplasia on the left in 1 case (0.021%). In the second group the greatest part of the cases were treated for neurological disturbances. We discuss the indications of different types of respiratory therapy and the complications as well. The survival rate was in the first group 59.3%, while in the second only 16.9%. Therefore the respiratory therapy seems to be more effective in the pulmonary diseases of the newborns. The mortality rate and the rate of severe complications were lower among inborn babies because of the early application of the respiratory therapy.