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DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
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A mesoporous organosilica nano-bowl with high DNA loading capacity - a potential gene delivery carrier
1School of Chemical Engineering, The University of Adelaide, SA 5005, Australia. s.qiao@adelaide.edu.au.
Nanoscale
|October 8, 2016
Abstract:
Mesoporous organosilica nanoparticles with a novel bowl-like morphology were synthesized. These nano-bowls possess uniform particle sizes around 180 nm and open cavities around 140 nm, which lead to higher loading capability for plasmid DNA than traditional silica-based nanoparticles. In vitro DNA transfection using these nano-bowls is demonstrated.
