A red fluorophore comprising a borinate-containing xanthene analogue as a polyol sensor

Area of Science:

• Organic Chemistry
• Analytical Chemistry
• Materials Science

Background:

• Borinate compounds are explored for their unique chemical properties.
• Fluorescent probes are crucial for sensitive detection in biological systems.
• Xanthene derivatives offer tunable optical properties.

Purpose of the Study:

• To develop a novel fluorescent sensor based on a xanthene derivative.
• To investigate the sensor's response to sugar molecules.
• To evaluate the sensor's performance in terms of pH resistance and quenching mechanisms.

Main Methods:

• Synthesis of a xanthene derivative with a borinate moiety.
• Spectroscopic analysis of fluorescence emission and quantum yield.
• Investigation of the interaction between the sensor and sugar molecules.
• Study of the effect of pH on fluorescence response.
• Analysis of quenching mechanisms with catechol.

Main Results:

• The synthesized xanthene derivative exhibited high-yield red fluorescence.
• Binding with sugar molecules induced a fluorescence change due to altered HOMO-LUMO gap.
• The sensor demonstrated pH resistance across a wide range.
• Catechol effectively quenched fluorescence via photoinduced electron transfer.

Conclusions:

• The borinate-containing xanthene derivative functions as an effective fluorescent sensor.
• Its polyol binding ability and pH resistance are promising for biological sensing.
• This work opens avenues for new chemical sensors in biological applications.