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Drug use during pregnancy in Hungary
1Department of Human Genetics and Teratology, National Institute of Hygiene, Budapest, Hungary.
Summary
Drug use during pregnancy is common, with over 90% of women reporting intake. Excluding supplements, nearly 30% used medications, primarily sex hormones and CNS-acting drugs.
Area of Science:
- Medical research
- Public health
- Epidemiology
Background:
- Understanding medication use during pregnancy is crucial for public health.
- The Hungarian Case-Control Surveillance of Congenital Abnormalities provides valuable data.
Purpose of the Study:
- To analyze the patterns of drug intake among pregnant women without congenital abnormalities.
- To identify the most frequently used drug categories during pregnancy.
Main Methods:
- Utilized data from the Hungarian Case-Control Surveillance of Congenital Abnormalities (1980-1985).
- Focused on a cohort of pregnant women who delivered unmalformed babies (negative controls).
- Categorized drug intakes, excluding vitamin, iron, and calcium supplements.
Main Results:
- Only 9.1% of 13,882 women reported no drug intake during pregnancy.
- Excluding supplements, 29.1% of women reported medication use.
- Most frequent drug classes included sex hormones (41.8%), CNS-acting drugs (38.8%), and cardiovascular drugs (33.9%).
Conclusions:
- A significant proportion of pregnant women utilize medications beyond basic supplements.
- Hormonal therapies and drugs affecting the central nervous and cardiovascular systems are prevalent.
- Further research is warranted to assess the safety and impact of these drug exposures.