A Glycolytic Solution for Pluripotent Stem Cells
Barbara Mlody1, Alessandro Prigione1
1Max Delbrueck Center for Molecular Medicine (MDC), D-13125 Berlin, Germany.
Cell Stem Cell
|October 8, 2016
Abstract:
Glycolysis is an essential component of cellular metabolism associated with pluripotent stem cells (PSCs). Two new papers, one by Gu et al. (2016) in this issue of Cell Stem Cell and one by Zhang et al. (2016) in Cell Reports, demonstrate that glycolytic flux is dynamically increased in human primed PSCs upon feeder-free cultivation or conversion into the naive state.


