Related Experiment Video
Updated: Mar 14, 2026

Promotion of Survival and Differentiation of Neural Stem Cells with Fibrin and Growth Factor Cocktails after Severe Spinal Cord Injury
Published on: July 27, 2014
Human ESC-Derived Interneurons Improve Major Consequences of Spinal Cord Injury
1Department of Neurological Surgery and Goodman Campbell Brain and Spine, Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Indianapolis, IN 46202, USA.
Abstract:
Beyond impaired motor and sensory function, neuropathic pain and loss of bladder control caused by spinal cord injuries (SCIs) can severely affect quality of life. In this issue of Cell Stem Cell, Fandel et al. (2016) show that transplanted human ESC-derived cells biased to produce inhibitory interneurons significantly improve pain and bladder function in rodent SCI models.

