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D-tyrosine affects aggregation behavior of Pantoea agglomerans
Jing Yang1, Jiajia Yu1, Jing Jiang1
1School of Life Science, Beijing Institute of Technology, Beijing, China.
Journal of Basic Microbiology
|October 8, 2016
Summary
D-tyrosine disassembles biofilms but promotes symplasmata formation in Pantoea agglomerans. This study reveals D-amino acids
Area of Science:
- Microbiology
- Biochemistry
Background:
- Biofilms are microbial communities encased in a self-produced matrix, contributing to bacterial persistence and pathogenicity.
- Pantoea agglomerans forms symplasmata, a unique multicellular structure with biofilm-forming capabilities.
- D-amino acids are known to disrupt bacterial biofilms by degrading the extracellular matrix.
Purpose of the Study:
- To investigate the impact of D-amino acids on biofilm and symplasmata structures in Pantoea agglomerans.
- To elucidate the specific effects of D-tyrosine on P. agglomerans YS19, a rice diazotrophic endophyte.
Main Methods:
- Treatment of P. agglomerans YS19 with D-tyrosine.
- Assessment of biofilm disassembly and symplasmata formation.
- Analysis of bacterial growth, motility, and protein expression (MalE, OmpF).
Main Results:
- D-tyrosine effectively disassembles biofilms formed by P. agglomerans YS19.
- D-tyrosine promotes the formation of symplasmata in P. agglomerans YS19.
- D-tyrosine enhances bacterial motility and inhibits the expression of MalE and OmpF proteins without affecting bacterial growth.
Conclusions:
- D-tyrosine exhibits differential effects on P. agglomerans multicellular structures, disassembling biofilms while promoting symplasmata.
- The findings expand the understanding of D-amino acid biological activities and provide new research avenues for symplasmata formation.
