Related Experiment Video
Updated: Mar 14, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Hypersensitivity to aspirin and urgent percutaneous coronary intervention: A therapeutic challenge
Tatiana Duarte1, Sara Gonçalves1, Catarina Sá1
1Serviço de Cardiologia, Centro Hospitalar de Setúbal, Setúbal, Portugal.
Abstract:
Hypersensitivity reactions to nonsteroidal anti-inflammatory drugs are common and five types of reactions have been defined. The prevalence of such reactions in patients with myocardial infarction is unclear, and so antiplatelet therapy in this population is a challenge. Various desensitization protocols have been developed but there are no specific guidelines for their use. The authors present the case of a patient with acute coronary syndrome and aspirin hypersensitivity referred for urgent coronary angiography. Aspirin desensitization therapy is safe and successful in many patients, but more randomized trials are needed to confirm its benefits in coronary artery disease patients.
Related Concept Videos
Acute Coronary Syndrome IV: Interprofessional Care
Cardiac Catheterization I: Pre-Procedure Overview
Acute Coronary Syndrome I: Introduction
Cardiac Catheterization II: Right Heart Catheterization
Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
Acute Coronary Syndrome V: Nursing Management

