Schizophrenia following withdrawal from chronic phenothiazine administration: a case report

The chronic administration of phenothiazines has come under increasing scrutiny recently, and the uncritical use of this form of treatment has been criticized. A case is presented illustrating the development of schizophrenia in a young adult following withdrawal from phenothiazines. As far as could be ascertained ther was no evidence of schizophrenia prior to withdrawal of phenothiazines. The possibility that withdrawal of phenothiazines may have aetiological significance in this case is discussed.