LSG vs OAGB-1 Year Follow-up Data-a Randomized Control Trial

Area of Science:

• Bariatric surgery
• Metabolic surgery
• Gastroenterology

Background:

• Laparoscopic sleeve gastrectomy (LSG) is a prevalent bariatric procedure.
• One anastomosis gastric bypass (OAGB) is an emerging, effective metabolic surgery.
• Comparative data on OAGB and LSG outcomes are essential for clinical decision-making.

Purpose of the Study:

• To compare the 1-year efficacy of OAGB versus LSG.
• Evaluate excess weight loss, complication rates, comorbidity resolution, and quality of life.
• Assess the comparative metabolic and surgical outcomes of two leading bariatric procedures.

Main Methods:

• Prospective randomized study comparing 100 LSG patients with 101 OAGB patients (2012-2015).
• Outcomes assessed included operative results, excess weight loss (%EWL), complications, comorbidity resolution (hypertension, T2DM), and quality of life (BAROS score).

Main Results:

• Mean BMI was comparable (OAGB: 44.31 kg/m², LSG: 43.75 kg/m²).
• %EWL at 1 year was similar (OAGB: 66.87%, LSG: 63.97%, p > 0.05).
• Diabetes remission favored OAGB (83.63% vs 76.58%), while hypertension remission was similar (OAGB: 64.15%, LSG: 66.07%). Quality of life scores were comparable (BAROS: OAGB 3.96, LSG 3.71).

Conclusions:

• No significant 1-year differences between OAGB and LSG in %EWL, hypertension remission, or quality of life.
• OAGB showed a marginal benefit in type 2 diabetes remission.
• Longer follow-up is necessary for definitive comparative results between OAGB and LSG.