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Pregnancy as a driver for melanoma.
G Richtig1,2,3, L Byrom4,5, R Kupsa1
1Department of Dermatology, Medical University of Graz, Auenbruggerplatz 8, A-8036, Graz, Austria.
The British Journal of Dermatology
|October 9, 2016
Summary
Pregnancy may influence melanoma development and growth, though it remains controversial. Early detection of suspicious moles during pregnancy is crucial, especially for women with numerous moles, to prevent advanced disease.
Area of Science:
- Dermatology
- Oncology
- Obstetrics
Background:
- The relationship between pregnancy and melanoma is debated.
- Pregnancy may potentially influence melanoma occurrence and progression.
- Case reports suggest aggressive melanoma courses during pregnancy.
Observation:
- A 36-year-old woman with multiple nevi developed two primary melanomas during pregnancy.
- Both melanomas were initially misinterpreted as dysplastic nevi.
- Lesion growth during pregnancy prompted their removal.
Findings:
- No metastatic disease was detected between 2010 and early 2017.
- Melanoma detection in pregnancy is challenging, especially when mimicking dysplastic nevi.
- Women with multiple nevi are at higher risk.
Implications:
- Pregnant women with numerous nevi should monitor for changes in size, shape, or color.
- Suspicious lesions require excision or careful monitoring, such as with sequential digital dermoscopy.
- Increased vigilance for melanoma in pregnant women with multiple nevi is recommended.
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