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Therapeutic Potential of Phytochemicals in Combination with Drugs for Cardiovascular Disorders
James Z Shen, Ting L J Ng, Wing S Ho1
1School of Life Sciences, MMW 604, CUHK. China.
Insights
Phytochemicals show therapeutic potential for cardiovascular diseases, offering complementary treatment options. Enhancing their delivery can improve efficacy, potentially combining them with traditional drugs for better outcomes.
Area of Science:
- Cardiovascular Science
- Pharmacology
- Natural Products Chemistry
Background:
- Cardiovascular disorders are a leading global cause of death.
- Key risk factors include hypertension, high LDL cholesterol, smoking, diabetes, and obesity.
- Conventional preventive measures and drugs exist but can be complemented by novel approaches.
Purpose of the Study:
- To review the therapeutic potential of phytochemicals in managing cardiovascular diseases.
- To explore strategies for enhancing the delivery efficiency of phytochemicals.
- To highlight natural products as complementary treatments for cardiovascular conditions.
Main Methods:
- Literature review of scientific studies on phytochemicals and cardiovascular health.
- Analysis of research on drug delivery systems for natural compounds.
- Synthesis of findings on the combined use of conventional drugs and natural products.
Main Results:
- Phytochemicals demonstrate significant therapeutic contributions to cardiovascular disease management.
- Oral administration is a common route, but delivery efficiency needs enhancement.
- Natural products offer promising complementary roles alongside therapeutic drugs.
Conclusions:
- Phytochemicals are valuable in cardiovascular disease management.
- Improving delivery systems is crucial for maximizing phytochemical efficacy.
- Combining phytochemicals with conventional therapies may enhance overall treatment effectiveness.
Abstract:
The incidence of cardiovascular disorders is increasing worldwide. Heart disease is the leading cause of death for both men and women. High blood pressure, high low-density lipoprotein cholesterol level, and smoking are key risk factors for heart disease. Other medical conditions such as diabetes, overweight, obesity and lifestyle can put people at a higher risk for coronary heart disease. The preventive measures based on the common drugs may help reduce the risk of cardiovascular diseases. The present review highlights the contributions of therapeutic potential of phytochemicals in management of cardiovascular diseases. However, the delivery efficiency of therapeutic agents can be enhanced in order to improve the efficacy of phytochemicals as a therapeutic agent. The oral administration of phytochemicals as therapeutic agents is a common approach. The review highlights the recent development of natural products for the complementary treatment of cardiovascular diseases. These findings indicate that the combination of therapeutic drugs and natural products may improve the treatment efficacy of therapeutic agents.
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