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Nomenclature for renal replacement therapy in acute kidney injury: basic principles
Mauro Neri1,2, Gianluca Villa1,3, Francesco Garzotto1
1Department of Nephrology, Dialysis and Transplantation, International Renal Research Institute of Vicenza, San Bortolo Hospital, Viale Rodolfi 37, Vicenza, 36100, Italy.
Critical Care (London, England)
|October 11, 2016
Summary
This consensus report harmonizes terminology for renal replacement therapy (RRT) in acute kidney injury (AKI). It details extracorporeal therapies and CRRT principles for consistent research and clinical application.
Area of Science:
- Nephrology
- Critical Care Medicine
- Biomedical Engineering
Background:
- Acute kidney injury (AKI) management relies on renal replacement therapy (RRT).
- Existing terminology for RRT, especially extracorporeal therapies, lacks standardization.
- A multidisciplinary consensus is needed to define RRT principles and nomenclature.
Purpose of the Study:
- To establish a harmonized nomenclature for the basic principles of extracorporeal renal replacement therapies.
- To provide clear definitions for components, techniques, and operations of RRT machines.
- To serve as guidelines for consistent terminology in future research and clinical practice.
Main Methods:
- Convening a multidisciplinary expert consensus conference.
- Adopting a "machine-centric" approach to define extracorporeal therapies.
- Detailing performance characteristics of membranes, filters, and fluid/solute transport.
- Focusing on continuous renal replacement therapies (CRRT) for critically ill AKI patients.
Main Results:
- A consensus on standardized nomenclature for RRT principles was reached.
- Detailed classifications and definitions of RRT devices and operations were established.
- The report emphasizes a machine-centric perspective for clarity in extracorporeal therapies.
Conclusions:
- Harmonized nomenclature is crucial for consistent RRT research and clinical application in AKI.
- Standardized definitions facilitate better understanding and comparison of different RRT techniques.
- This consensus report provides a foundational framework for future terminology in the field.
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