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Can low BMI Chinese patients with type 2 diabetes benefit from laparoscopic Roux-en-Y gastric bypass surgery?
Guohui Wang1, Liyong Zhu2, Weizheng Li2
1Centre of Experimental Medicine, Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Background:
The efficacy of laparoscopic Roux-en-Y gastric bypass (LRYGB) in type 2 diabetes mellitus (T2D) is closely associated with the preoperative body mass index (BMI) of the patient. There is a lack of long-term and large sampling evidence on the efficacy of LRYGB in T2D patients with low BMI in China.
Objectives:
This retrospective study aimed to evaluate the efficacy of surgical treatment in a Chinese population with T2D (especially patients with BMI<27.5 kg/m2).
Setting:
University-affiliated hospital, China METHODS: Seventy-eight patients with T2D were included in the study and evaluated before and after LRYGB surgery. No patients were lost to follow-up at any time points.
Results:
Thirty-eight T2D patients with BMI≥27.5 kg/m2 in group 1 (high BMI group) had significant improvements in waist circumference, blood glucose levels, homeostasis model assessment-insulin resistance index, and C-peptide levels after LRYGB (P<.05). Forty T2D patients with BMI<27.5 kg/m2 in group 2 (low BMI group, including 19 T2D patients with BMI<25 kg/m2) had significant improvements in waist circumference and waist-to-hip ratio after LRYGB (P< .05).
Conclusions:
LRYGB surgery may be beneficial in T2D patients with BMI<27.5 kg/m2 in China.
