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Updated: Mar 13, 2026

Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer
Published on: May 10, 2024
Colon cancer targeting using conjugates biomaterial 5-flurouracil
Soleiman Jaferian1, Babak Negahdari2, Ali Eatemadi3
1Department of Internal Medicine, Lorestan University of Medical Sciences, Khoramabad, Iran.
Abstract:
There has been several research works on the development of an oral delivery system to deliver cytotoxic and chemo preventive agents directly at the targeted site of action with reduced unwanted side effects. The efficacy of the site-specific delivery system of a drug to colon has been proven to increase the drugs concentration at the target site, and thus requires a reduced dose of the drug with minimized side effects. This review includes discussion of the delivery systems of 5-FU using biodegradable materials and some significant outcomes in the pre-clinical development of 5-fluorouracil carriers for the colon cancer.
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