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Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
Published on: August 25, 2018
Development, validation and application of a device to measure e-cigarette users' puffing topography
Anthony Cunningham1, Sandra Slayford1, Carl Vas1
1Research and Development, British American Tobacco (Investments) Ltd., Regents Park Road, Southampton SO15 8TL, United Kingdom.
Understanding electronic cigarette (e-cigarette) use is crucial. Puffing topography reveals that e-cigarette design significantly impacts user behavior and aerosol exposure, meaning results aren't universal across devices.
Area of Science:
- Public Health
- Toxicology
- Consumer Product Safety
Background:
- The increasing popularity and evolution of electronic cigarettes (e-cigarettes) necessitate understanding user behavior and aerosol exposure.
- Previous research has not fully elucidated how different e-cigarette designs influence user puffing patterns.
Purpose of the Study:
- To measure and analyze consumer puffing topography for various e-cigarette types.
- To determine if product characteristics influence how users interact with e-cigarettes.
- To provide insights for standardizing e-cigarette testing protocols.
Main Methods:
- Adapted a cigarette puffing topography device for e-cigarette use and validated it with air and aerosol.
- Recruited 60 vapers using rechargeable 'cig-a-like' or button-activated e-cigarettes.
- Measured puff duration, puff volume, and inter-puff intervals during ad-libitum use over two sessions.
Main Results:
- The adapted puffing topography device demonstrated high accuracy in measuring puff volumes for both air and e-cigarette aerosol.
- While puff durations were similar, mean puff volumes and inter-puff intervals significantly differed between 'cig-a-like' and button-activated e-cigarettes.
- These variations indicate that e-cigarette product characteristics directly influence user puffing topography.
Conclusions:
- E-cigarette product design significantly impacts user puffing topography, affecting aerosol delivery and exposure.
- Findings highlight that puffing patterns vary considerably across different e-cigarette types.
- Standardizing e-cigarette testing requires a thorough understanding of how product characteristics influence user behavior.
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