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Corneal Ring Infiltrates Caused by Serratia marcescens in a Patient with Human Immunodeficiency Virus

Winai Chaidaroon1, Sumet Supalaset1

  • 1Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Case Reports in Ophthalmology
|October 11, 2016
PubMed
Abstract

Insights

Serratia marcescens caused corneal ring infiltrates in a contact lens wearer with human immunodeficiency virus (HIV-1). Intensive topical antibiotic treatment yielded favorable outcomes for this severe keratitis case.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Contact lens wear is a significant risk factor for microbial keratitis.
  • Human immunodeficiency virus (HIV-1) infection can predispose individuals to opportunistic infections, including ocular infections.

Observation:

  • A case study identified corneal ring infiltrates in a 29-year-old male contact lens wearer with a history of HIV-1 infection.
  • The patient presented with blurred vision, redness, and ring-shaped corneal infiltrates in the left eye, with initial visual acuity of hand movement in both eyes.

Findings:

  • Corneal scrapings and contact lens cultures confirmed infection by *Serratia marcescens*.
  • The patient's corneal ulcer responded well to topical gentamycin sulfate treatment.
  • Despite treatment, the final visual acuity remained hand movement.

Implications:

  • This case highlights *Serratia marcescens* as a causative agent of corneal ring infiltrates in immunocompromised contact lens wearers.
  • Prompt diagnosis and intensive topical antibiotic therapy are crucial for managing *S. marcescens* keratitis in HIV-1 patients.
  • Contact lens hygiene and regular eye examinations are essential for individuals with HIV-1 to prevent severe ocular infections.
Keywords:
Contact lensCorneal ring infiltratesHuman immunodeficiency virusSerratia marcescens

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