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Cerebral Erdheim-Chester disease: persistent enhancement with Gd-DTPA on MR images
R D Tien1, R C Brasch, D E Jackson
1Department of Radiology, University of California San Francisco 94143.
Radiology
|September 1, 1989
Abstract:
A case of Erdheim-Chester disease with intracerebral masses containing characteristic lipid-laden histiocytes is presented. These unusual lesions remained enhanced on magnetic resonance images obtained 8 days after injection of gadolinium diethylenetriaminepentaacetic acid (DTPA) dimeglumine. Chemical analysis of a biopsy specimen revealed a high concentration of gadolinium. Findings suggest that the Gd-DTPA complex or possibly a gadolinium-containing metabolite may be retained for extended periods in this unusual type of histiocytic lesion.