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The Tumor Microenvironment

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...

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Related Experiment Video

Updated: Mar 13, 2026

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

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Extensive marrow infiltration in epidural Ewing sarcoma

Huma Mansoori¹, Bushra Moiz¹

¹Department of Haematology, Aga Khan University Hospital, Karachi, Pakistan.

|October 11, 2016

Summary

No abstract available in PubMed .

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