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Updated: Mar 13, 2026

Energy Dispersive X-ray Tomography for 3D Elemental Mapping of Individual Nanoparticles
Published on: July 5, 2016
Visualising coordination chemistry: fluorescence X-ray absorption near edge structure tomography
S A James1, R Burke2, D L Howard1
1Australian Synchrotron, 800 Blackburn Rd, Clayton 3168, Australia. martin.dejonge@synchrotron.org.au.
Abstract:
Coordination chemistry underlies the structure/function of biological metal complexes. Contextualising this chemical information within an organism's physiology is critical for enhancing the understanding of bioinorganic chemistry but few high-fidelity probes are available. Here we develop fluorescence X-ray absorption near-edge structure tomography as a means for studying the spatial arrangement of biological coordination chemistry within intact organisms, and demonstrate the approach by mapping the distribution of cuprous and cupric complexes within Drosophila melanogaster.
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