Optically assembled droplet interface bilayer (OptiDIB) networks from cell-sized microdroplets
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Updated: Mar 13, 2026
Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer
Published on: April 19, 2021
Mark S Friddin1, Guido Bolognesi2, Yuval Elani1
1Department of Chemistry, Imperial College London, Exhibition Road South Kensington, London, SW7 2AZ, UK. o.ces@imperial.ac.uk and Institute of Chemical Biology, Imperial College London, Exhibition Road South Kensington, London, SW7 2AZ, UK.
Abstract:
We report a new platform technology to systematically assemble droplet interface bilayer (DIB) networks in user-defined 3D architectures from cell-sized droplets using optical tweezers. Our OptiDIB platform is the first demonstration of optical trapping to precisely construct 3D DIB networks, paving the way for the development of a new generation of modular bio-systems.
