[Second neoplasms in Hodgkin's disease]

Today, excellent therapeutic results are obtained in Hodgkin's disease however, they may be obscured by the development of long term complications due to the treatment given including second neoplasias. Out of the total of 250 cases of Hodgkin's disease reviewed during 19 years we found 13 secondary neoplasias. All the patients received alkylating drugs and in 10, both chemo and radiotherapy were associated. The average interval of time was 48 months. Bronchopulmonary carcinomas and acute leukemias were the malignancies most often encountered.