Related Experiment Video
Updated: Mar 13, 2026
Application of Mid-Pancreatectomy with End-to-End Anastomosis in Pancreatic Benign Tumors
Published on: February 9, 2024
[Total pancreatectomy for pancreatic cancer]
Yu I Patyutko1, N E Kudashkin1, A G Kotel'nikov1
1Blokhin Russian Cancer Research Center, Moscow, Russia.
Aim:
to determine the indications and to evaluate early and long-term outcomes of total pancreatectomy for pancreatic cancer.
Material And Methods:
Treatment of 29 patients who underwent one- and two-stage pancreatectomy for different malignancies was analyzed.
Results:
Median of surgery duration and intraoperative blood loss was 280 min and 2200 ml respectively. Postoperative complications were observed in 9 (31%) patients. There were 2 (6.9%) deaths. 1- and 3-year overall actual survival was 61% and 16% respectively in case of ductal adenocarcinoma. Median was 18 months. Patients after surgery for primary multiple lesion (cancer of pancreatic body-tail and major duodenal papilla), pancreatic metastases of renal cancer, mucinous cystadenoma and neuroendocrine cancer are still alive. Follow-up periods are 4, 49, 49 and 65 months respectively.
Conclusion:
Total pancreatectomy is difficult intervention followed by severe metabolic disorders. However it can improve long-term survival with acceptable incidence of postoperative complications and quality of life if clear indications for surgery are present.
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