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Updated: Mar 13, 2026

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Comparing Breast Screening Protocols: Inserting Catch Trials Does Not Improve Sensitivity over Double Screening.

Weijia Chen1, Piers D L Howe1

  • 1School of Psychological Sciences, University of Melbourne, Parkville, Victoria, Australia.

Plos One
|October 11, 2016
PubMed
Summary
This summary is machine-generated.

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A new breast screening protocol, the catch trial (CT) protocol, was tested against Australia's current double screener (DS) protocol. The CT protocol did not improve cancer detection sensitivity and is not recommended for clinical trials.

Area of Science:

  • Radiology
  • Medical Imaging
  • Cancer Detection

Background:

  • Breast screening is crucial for early breast cancer detection.
  • Low tumour prevalence in mammograms can lead to missed diagnoses (prevalence effect).
  • A novel catch trial (CT) protocol was developed to improve tumour detection rates.

Purpose of the Study:

  • To evaluate if the catch trial (CT) protocol enhances radiologist sensitivity compared to the double screener (DS) protocol.
  • To assess if the CT protocol reduces missed tumours without increasing radiologist workload.

Main Methods:

  • Two laboratory-based experiments were conducted.
  • The catch trial (CT) protocol's sensitivity (d') was compared to the double screener (DS) protocol.
  • Experiments used varying stimuli, with the second using more realistic tumour representations.

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Main Results:

  • The first experiment showed a criterion shift but unclear sensitivity differences between CT and DS protocols.
  • The second experiment, using realistic stimuli, found no convincing evidence of increased sensitivity with the CT protocol.
  • Both hit and false alarm rates increased in the CT protocol, suggesting similar sensitivity to the DS protocol.

Conclusions:

  • The catch trial (CT) protocol is unlikely to improve sensitivity over the current double screener (DS) protocol.
  • The study does not recommend the CT protocol for clinical trial implementation.
  • Further research may be needed to explore alternative methods for improving breast cancer detection in screening programs.