Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Osteochondral Autograft Transfer for Focal Osteochondral Defects of the Knee: Indications, Technique, Outcomes, and Future Directions.

The Journal of bone and joint surgery. American volume·2026
Same author

A novel knee joint laxity measurement device in mice.

Journal of biomechanics·2026
Same author

Open capsular shift with Achilles allograft augmentation for multidirectional shoulder instability: long-term outcomes and implications for patients with Ehlers-Danlos syndrome.

Journal of shoulder and elbow surgery·2026
Same author

Medical Tourism for Regenerative Medicine Treatments: Legitimate Therapy or Snake Oil?

The American journal of sports medicine·2026
Same author

Clinical Utility of the Moving Valgus Stress Test and Milking Maneuver for Medial Ulnar Collateral Ligament Injuries of the Elbow.

The American journal of sports medicine·2026
Same author

Podium Abstracts Presented at the 2025 Annual Meeting of the Arthroscopy Association of North America.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association·2026

Related Experiment Video

Updated: Mar 13, 2026

Development of a Rabbit Chronic-Like Rotator Cuff Injury Model for Study of Fibrosis and Muscular Fatty Degeneration
05:20

Development of a Rabbit Chronic-Like Rotator Cuff Injury Model for Study of Fibrosis and Muscular Fatty Degeneration

Published on: March 31, 2023

1.9K

Animal models for rotator cuff repair.

Amir Lebaschi1, Xiang-Hua Deng1, Jianchun Zong1

  • 1Tissue Engineering, Repair, and Regeneration Program.

Annals of the New York Academy of Sciences
|October 11, 2016
PubMed
Summary

Animal models are crucial for studying rotator cuff (RC) injuries. This review highlights the utility of small animal models, particularly the murine model, for advancing rotator cuff tendon repair research.

Keywords:
animal modelmouserepairrotator cuff

More Related Videos

Arthroscopic Management of Massive Irreparable Rotator Cuff Tears: Whole Rotator Cable Reconstruction Using Proximal Biceps Tendon Autograft
07:22

Arthroscopic Management of Massive Irreparable Rotator Cuff Tears: Whole Rotator Cable Reconstruction Using Proximal Biceps Tendon Autograft

Published on: June 6, 2025

802
Rat Model of Adhesive Capsulitis of the Shoulder
04:46

Rat Model of Adhesive Capsulitis of the Shoulder

Published on: September 28, 2018

8.0K

Related Experiment Videos

Last Updated: Mar 13, 2026

Development of a Rabbit Chronic-Like Rotator Cuff Injury Model for Study of Fibrosis and Muscular Fatty Degeneration
05:20

Development of a Rabbit Chronic-Like Rotator Cuff Injury Model for Study of Fibrosis and Muscular Fatty Degeneration

Published on: March 31, 2023

1.9K
Arthroscopic Management of Massive Irreparable Rotator Cuff Tears: Whole Rotator Cable Reconstruction Using Proximal Biceps Tendon Autograft
07:22

Arthroscopic Management of Massive Irreparable Rotator Cuff Tears: Whole Rotator Cable Reconstruction Using Proximal Biceps Tendon Autograft

Published on: June 6, 2025

802
Rat Model of Adhesive Capsulitis of the Shoulder
04:46

Rat Model of Adhesive Capsulitis of the Shoulder

Published on: September 28, 2018

8.0K

Area of Science:

  • Orthopedics
  • Musculoskeletal Research
  • Biomedical Engineering

Background:

  • Rotator cuff (RC) injuries cause significant pain and functional impairment.
  • Developing effective treatments for RC pathologies requires advanced research methodologies.
  • Animal models are essential for understanding RC injuries, mimicking anatomical, biomechanical, and molecular aspects.

Purpose of the Study:

  • To review existing animal models for rotator cuff (RC) research.
  • To emphasize the potential of small animal models, specifically the murine model, for future investigations.
  • To discuss the evolving landscape of musculoskeletal (MSK) research models.

Main Methods:

  • Review of existing literature on animal models for RC injuries.
  • Analysis of the suitability of different animal models based on anatomical and functional similarity.
  • Evaluation of advancements in molecular techniques and microsurgery impacting small animal model applicability.

Main Results:

  • Traditionally, larger animals were preferred due to anatomical similarity and surgical feasibility.
  • Advancements in molecular biology and microsurgery have enhanced the utility of small animal models.
  • The murine model shows promise as a valuable tool for RC tendon repair research.

Conclusions:

  • Small animal models, especially the murine model, offer a viable and increasingly applicable platform for RC research.
  • Continued development and refinement of these models are critical for advancing rotator cuff tendon repair strategies.
  • The murine model's potential warrants further investigation for its role in preclinical studies of RC pathologies.