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[Antirreflux ureteral catheters.]

F Soria1, J E de la Cruz1, E Morcillo1

  • 1Unidad de Endoscopia de la Fundación Centro de Cirugía de Mínima Invasión Jesús Usón. Cáceres. España.

Archivos Espanoles De Urologia
|October 12, 2016
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Summary
This summary is machine-generated.

Double-J ureteral stents cause side effects in 90% of patients due to design and materials. New anti-reflux stent designs show promise in animal models but lack clinical evidence for widespread adoption.

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Area of Science:

  • Urology
  • Biomaterials Science
  • Medical Device Engineering

Background:

  • Double-J ureteral stents are associated with significant patient side effects (up to 90%), primarily due to their design and material composition.
  • Vesicoureteral reflux and bladder trigone irritation are key factors contributing to ureteral stent morbidity.
  • Existing stent designs often lead to complications, necessitating the development of improved anti-reflux alternatives.

Purpose of the Study:

  • To review the development and evaluation of anti-reflux ureteral stent designs.
  • To assess novel stent prototypes aimed at reducing vesicoureteral reflux (VUR) and associated complications.
  • To highlight the current gap in clinical evidence for advanced ureteral stent technologies.

Main Methods:

  • Review of existing literature on double-J ureteral stent complications and anti-reflux designs.
  • Analysis of early-stage (animal model) evaluations of novel stent prototypes.
  • Assessment of the clinical implementation status of new anti-reflux stent technologies.

Main Results:

  • Early anti-reflux designs, like those with polymeric membranes, showed some efficacy but lacked statistical significance.
  • Recent prototypes, including a valve-attached stent and an intra-ureteral design, demonstrated VUR reduction in animal models.
  • Despite promising preclinical results, these advanced designs are not yet standard clinical practice.

Conclusions:

  • Current double-J ureteral stent designs contribute to substantial patient morbidity.
  • Novel anti-reflux stent designs offer potential solutions to reduce complications like VUR.
  • Further clinical trials and scientific evidence are required to support the adoption of these innovative stents in healthcare settings.