Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Phylum Actinobacteria01:30

Bacterial Phylum Actinobacteria

804
Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...
804
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

1.9K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
1.9K
Bacterial Phylum Tenericutes01:24

Bacterial Phylum Tenericutes

565
The phylum Tenericutes, which includes the single class Mollicutes, comprises bacteria that lack cell walls. The term "Mollicutes" derives from the Latin word mollis, meaning "soft." These organisms are among the smallest known and are commonly referred to as mycoplasmas due to the prominence of the genus Mycoplasma, which includes well-known human pathogens. Despite their inability to stain gram-positively (a result of their lack of cell walls), mycoplasmas are phylogenetically related to the...
565
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

3.3K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
3.3K
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

1.2K
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.2K
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

1.3K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Environmental reservoirs of carbapenem-resistant organisms in the intensive care unit: a multicenter longitudinal study in two middle-income country hospitals.

Antimicrobial resistance and infection control·2026
Same author

<i>Legionella</i> 5S rRNA PCR melting temperature analysis discriminates high-risk species associated with disease severity.

Journal of clinical microbiology·2026
Same author

Comparison of laboratory-developed methods for aztreonam plus ceftazidime-avibactam antimicrobial susceptibility testing for metallo-beta-lactamase-producing Enterobacterales.

Journal of clinical microbiology·2026
Same author

Recurrent cross-reactivity between <i>Candida tropicalis</i> and <i>Candida parapsilosis</i> on the BIOFIRE FilmArray Blood Culture Identification 2 panel.

Journal of clinical microbiology·2026
Same author

Imaging characteristics, yield of computed tomography, and clinical outcomes of central nervous system nocardiosis.

Infection·2026
Same author

Detecting healthcare-associated transmission and antifungal resistance in <i>Candida auris</i> via whole genome sequencing.

Journal of clinical microbiology·2026

Related Experiment Video

Updated: Mar 13, 2026

Identification of Mycobacterium Species by DNA Microarray Chip Method
06:27

Identification of Mycobacterium Species by DNA Microarray Chip Method

Published on: June 24, 2025

708

Mycobacteria.

Patricia J Simner1, Gail L Woods2, Nancy L Wengenack3

  • 1Division of Clinical Microbiology, Department of Pathology, Johns Hopkins University Medical Center, Baltimore, MD 21287.

Microbiology Spectrum
|October 12, 2016
PubMed
Summary
This summary is machine-generated.

Immunocompromised individuals face higher risks of mycobacterial infections. Advances in diagnostics like PCR and mass spectrometry enable faster identification and drug resistance testing for better patient outcomes and tuberculosis control.

More Related Videos

Analysis of the Lipid Composition of Mycobacteria by Thin Layer Chromatography
07:42

Analysis of the Lipid Composition of Mycobacteria by Thin Layer Chromatography

Published on: April 16, 2021

9.5K
Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes
08:34

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes

Published on: September 27, 2018

9.2K

Related Experiment Videos

Last Updated: Mar 13, 2026

Identification of Mycobacterium Species by DNA Microarray Chip Method
06:27

Identification of Mycobacterium Species by DNA Microarray Chip Method

Published on: June 24, 2025

708
Analysis of the Lipid Composition of Mycobacteria by Thin Layer Chromatography
07:42

Analysis of the Lipid Composition of Mycobacteria by Thin Layer Chromatography

Published on: April 16, 2021

9.5K
Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes
08:34

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes

Published on: September 27, 2018

9.2K

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Clinical Diagnostics

Background:

  • Immunocompromised hosts are highly susceptible to Mycobacterium tuberculosis complex (MTB-C) and nontuberculous mycobacteria (NTM).
  • While MTB-C is a major pathogen, NTM infections cause significant disease in immunocompromised individuals, leading to substantial morbidity and mortality.
  • Rapid and accurate mycobacterial species identification and drug susceptibility testing are crucial for effective patient management.

Purpose of the Study:

  • To review recent advancements in mycobacterial diagnostics.
  • To highlight the impact of rapid diagnostic methods on patient care and tuberculosis control.

Main Methods:

  • Review of diagnostic technologies including immunodiagnostics (interferon gamma release assay), microscopy (LED), culture (automated broth systems), identification (PCR, sequencing, MALDI-TOF MS), and susceptibility testing (molecular detection of resistance).

Main Results:

  • Significant progress in mycobacterial diagnostics over the past two decades.
  • New methods offer improved speed and sensitivity for identification and drug resistance detection.

Conclusions:

  • Implementing rapid and sensitive diagnostic methods in mycobacterial laboratories significantly improves patient care.
  • These advancements are vital for managing mycobacterial infections in immunocompromised hosts and controlling tuberculosis transmission.