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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
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The ABCs of managing systolic heart failure: Past, present, and future

Ike Stanley Okwuosa1, Oluseyi Princewill1, Chiemeke Nwabueze2

  • 1Division of Cardiology, The Johns Hopkins Hospital, Baltimore, MD, USA.

Cleveland Clinic Journal of Medicine
|October 12, 2016
PubMed

Insights

Current heart failure management is complex. This review provides an evidence-based approach to updated heart failure (HF) treatments, incorporating new drugs and devices since the 2013 guidelines.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Pharmacology

Background:

  • Heart failure (HF) management is intricate and continually advancing.
  • The last comprehensive evidence-based guidelines from the American College of Cardiology and American Heart Association (ACC/AHA) were published in 2013.
  • Significant advancements in pharmacotherapy and device-based therapies have emerged since 2013.

Purpose of the Study:

  • To present a contemporary, evidence-based strategy for managing heart failure.
  • To synthesize recent developments in HF treatment modalities.
  • To guide clinicians in applying updated evidence to patient care.

Main Methods:

  • Systematic review of recent clinical trials and guideline updates.
  • Analysis of pharmacological interventions, including newly approved agents.
  • Evaluation of novel device therapies for heart failure.

Main Results:

  • Updated recommendations for guideline-directed medical therapy (GDMT) in HF.
  • Integration of new drug classes (e.g., SGLT2 inhibitors, ARNIs) into HF management algorithms.
  • Consideration of advanced device therapies (e.g., CRT, ICDs) based on latest evidence.

Conclusions:

  • Current heart failure management requires incorporating recent evidence on novel therapies.
  • A multidisciplinary, evidence-based approach is crucial for optimizing outcomes in heart failure patients.
  • Adherence to updated guidelines ensures the best possible patient care and prognosis.

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