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Pregnancy in patients with tuberculosis: a TBNET cross-sectional survey
Graham H Bothamley1, Cordula Ehlers2, Irina Salonka3
1Department of Respiratory Medicine, Homerton University Hospital, London, E9 6SR, UK. graham.bothamley@homerton.nhs.uk.
Background:
Objectives: To determine whether the incidence of tuberculosis with pregnancy is more common than would be expected from the crude birth rate; to see whether there is significant delay in the diagnosis of tuberculosis during pregnancy.
Method:
Design: A cross-sectional survey.
Setting:
13 tuberculosis clinics within different European countries and the USA.
Population/Sample:
All patients with tuberculosis seen at these clinics for a period > 1 year.
Instrument:
Questionnaire survey based on continuous data collection.
Main Outcome Measures:
number and proportion of women with tuberculosis who were pregnant; timing of diagnosis in relation to pregnancy, including those who were pregnant or delivered in the 3 months prior to the diagnosis of TB and those who developed TB within 3 months after delivery.
Results:
Pregnancy occurred in 224 (1.5 %) of 15,217 TB patients and followed the expected rate predicted from the crude birth rate for the clinic populations. TB was diagnosed more commonly in the 3 months after delivery (n = 103) than during pregnancy (n = 68; χ 2 = 25.1, P < 0.001).
Conclusions:
TB is diagnosed more frequently after delivery, despite variations in local TB incidence and healthcare systems.
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