Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Detection and Classification of Pancreatic Cancer Nodules on CT Images using U-Net and Ensemble Models.

Current medical imaging·2026
Same author

Engineering early immune resilience in islet transplantation.

Trends in pharmacological sciences·2026
Same author

Combinatorial histone modifications direct ATP-dependent chromatin remodeling by NURF to promoter-proximal nucleosomes.

Nucleic acids research·2026
Same author

Operon™ Platform-Enabled for Cardiometabolic Biomarker Screening and Precision Treatment Strategies: A Type 2 Diabetes-Centered Review with Cardiovascular Extension.

International journal of molecular sciences·2026
Same author

Use of Small Organic Molecules to Improve Pancreatic Beta Cell Resilience to IAPP-Induced Proteotoxic Stress.

International journal of molecular sciences·2026
Same author

AI-derived therapeutic development of a serotonin receptor-targeting drug for the treatment of opioid use disorder.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Transplantation of human umbilical mesenchymal stromal cells attenuates heart failure progression in a rat model.

Cell transplantation·2026
Same journal

Three-dimensionally printed mesoporous bioactive glass for craniomaxillofacial bone regeneration: Material evolution, functional mechanisms, and clinical translation.

Cell transplantation·2026
Same journal

Hotspots and trends in stem cell therapy for ligament injuries: A bibliometric analysis (2001-2025).

Cell transplantation·2026
Same journal

Amniotic epithelial cells enhance islet engraftment by suppressing early inflammation in intraportal transplantation.

Cell transplantation·2026
Same journal

Cdc42-Modified BMSC-Derived exosomes promote acellular nerve allografts to bridge sciatic nerve defects.

Cell transplantation·2026
Same journal

Organ-on-a-chip as a next-generation tool in drug development: A bibliometric and patent analysis.

Cell transplantation·2026
See all related articles

Related Experiment Video

Updated: Mar 13, 2026

Alginate Encapsulation of Pluripotent Stem Cells Using a Co-axial Nozzle
07:13

Alginate Encapsulation of Pluripotent Stem Cells Using a Co-axial Nozzle

Published on: July 2, 2015

13.5K

Developing a Rapid Algorithm to Enable Rapid Characterization of Alginate Microcapsules.

Ka Hei Chan, Rahul Krishnan, Michael Alexander

    Cell Transplantation
    |October 13, 2016
    PubMed
    Summary
    This summary is machine-generated.

    An automated image analysis algorithm was developed to characterize microencapsulated islets, improving quality control for type 1 diabetes (T1D) research and biomaterial design.

    More Related Videos

    Generation of Alginate Microspheres for Biomedical Applications
    10:33

    Generation of Alginate Microspheres for Biomedical Applications

    Published on: August 12, 2012

    22.0K
    Author Spotlight: Advancing Therapeutics with Biocompatible Sodium Alginate Hydrogel Microspheres
    07:24

    Author Spotlight: Advancing Therapeutics with Biocompatible Sodium Alginate Hydrogel Microspheres

    Published on: June 7, 2024

    3.2K

    Related Experiment Videos

    Last Updated: Mar 13, 2026

    Alginate Encapsulation of Pluripotent Stem Cells Using a Co-axial Nozzle
    07:13

    Alginate Encapsulation of Pluripotent Stem Cells Using a Co-axial Nozzle

    Published on: July 2, 2015

    13.5K
    Generation of Alginate Microspheres for Biomedical Applications
    10:33

    Generation of Alginate Microspheres for Biomedical Applications

    Published on: August 12, 2012

    22.0K
    Author Spotlight: Advancing Therapeutics with Biocompatible Sodium Alginate Hydrogel Microspheres
    07:24

    Author Spotlight: Advancing Therapeutics with Biocompatible Sodium Alginate Hydrogel Microspheres

    Published on: June 7, 2024

    3.2K

    Area of Science:

    • Biomedical Engineering
    • Immunology
    • Endocrinology

    Background:

    • Islets of Langerhans secrete insulin, crucial for glucose metabolism.
    • Type 1 diabetes (T1D) results from autoimmune destruction of islets.
    • Islet transplantation is limited by immunosuppression needs; microencapsulation offers a potential solution.

    Purpose of the Study:

    • To develop an automated image analysis algorithm for characterizing microencapsulated islets.
    • To reduce observer bias and improve efficiency in assessing microcapsule morphology and encapsulation efficiency.

    Main Methods:

    • Development of a novel image analysis algorithm.
    • Application of the algorithm to analyze microencapsulated islets for size, shape, circularity, and distortion.
    • Validation of the algorithm's ability to characterize hundreds of microcapsules with minimal bias.

    Main Results:

    • The algorithm successfully characterized microencapsulated islets with minimal observer bias.
    • Automated analysis significantly improved efficiency and reduced errors in quality control.
    • The algorithm demonstrated adaptability to similar nano- or microencapsulation technologies.

    Conclusions:

    • Automated image analysis is crucial for efficient and unbiased characterization of microencapsulated islets.
    • This technology can enhance quality control in islet encapsulation for T1D therapies.
    • The algorithm can improve biomaterial device design and success rates in preclinical studies.