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Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Ezocgabine or retigabine, an antiepileptic drug of remarkable efficacy, has revolutionized the management of seizures. It is a potassium channel activator, explicitly targeting the family of Q subtype potassium channels. It enhances the transmembrane potassium currents, regulating neuronal excitability. This action stabilizes the resting membrane potential, a pivotal factor in mitigating the hyperexcitability that characterizes epilepsy.
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Gefitinib and Sonidegib.

Corey J Medler¹, J Aubrey Waddell¹, Dominic A Solimando¹

¹Corey J. Medler is a doctor of pharmacy candidate at the University of Tennessee College of Pharmacy .

Hospital Pharmacy

|October 13, 2016

Summary

Pharmacists must understand complex cancer chemotherapy regimens and toxic agents. This review covers preparation, dispensing, and administration of antineoplastic therapy and related agents.

Area of Science:

Oncology Pharmacy
Chemotherapy Administration

Background:

Cancer chemotherapy involves complex regimens and highly toxic agents requiring specialized pharmacist knowledge.
This review focuses on the practical aspects of antineoplastic therapy, including preparation, dispensing, and administration.

Discussion:

The safe and effective use of chemotherapy necessitates a thorough understanding of both established and investigational antineoplastic agents.
Pharmacists play a critical role in managing the complexities of cancer treatment.

Key Insights:

Familiarity with complicated chemotherapy regimens is essential for pharmacists.
Knowledge of highly toxic agents used in cancer treatment is crucial for safe patient care.

Outlook:

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Future discussions will address emerging antineoplastic agents and advanced chemotherapy administration techniques.

Continued education and collaboration are vital for optimizing oncology pharmacy practice.