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Updated: Mar 13, 2026
Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera
Published on: January 30, 2020
Characterization of "γ-Eye": a Low-Cost Benchtop Mouse-Sized Gamma Camera for Dynamic and Static Imaging Studies
Maria Georgiou1, Eleftherios Fysikopoulos2, Konstantinos Mikropoulos3
1BET Solutions, R & D, Athens, Greece. mgeorgiou@betsolutions.gr.
Purpose:
Several preclinical imaging systems are commercially available, but their purchase and maintenance costs make them unaffordable for the majority of small- and medium-sized groups. Taking into account the needs of average users, we developed "γ-eye", a mouse-sized, benchtop γ-camera suitable for in vivo scintigraphic imaging.
Procedures:
The γ-eye is based on two position-sensitive photomultiplier tubes, coupled to a CsI(Na) pixelated scintillator and a low-energy lead collimator with parallel hexagonal holes.
Results:
The spatial resolution of the system is 2 mm at 0 mm. The energy resolution is 26 % at 140 keV and the maximum recorded sensitivity 210 cps/MBq. The system was evaluated in a proof-of-concept animal study, using three different clinical Tc-99m-labeled radiopharmaceuticals. Phantom and animal studies demonstrate its ability to provide semiquantitative results even for short scans.
Conclusions:
Systems' performance, dimensions, and cost make γ-eye a unique solution for efficient whole-body mouse nuclear imaging.
