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Updated: Mar 13, 2026

Using the GAL4-UAS System for Functional Genetics in Anopheles gambiae
Published on: April 15, 2021
The GAL4 System: A Versatile System for the Manipulation and Analysis of Gene Expression
Elizabeth E Caygill1, Andrea H Brand2
1The Gurdon Institute and Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 1QN, UK.
Abstract:
Since its introduction in 1993, the GAL4 system has become an essential part of the Drosophila geneticist's toolkit. Widely used to drive gene expression in a multitude of cell- and tissue-specific patterns, the system has been adapted and extended to form the basis of many modern tools for the manipulation of gene expression in Drosophila and other model organisms.
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