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Related Concept Videos

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

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Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
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Related Experiment Video

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Two-axis polydimethylsiloxane-based electromagnetic microelectromechanical system scanning mirror for optical

Sehui Kim1, Changho Lee1, Jin Young Kim1

  • 1Pohang University of Science and Technology (POSTECH), Department of Creative IT Engineering, 77 Cheongam-ro, Pohang, Republic of Korea.

Journal of Biomedical Optics
|October 13, 2016
PubMed
Summary

Researchers developed a low-cost, compact two-axis polydimethylsiloxane-based microelectromechanical system (MEMS) scanning mirror. This innovation enables faster clinical translation and commercialization of miniaturized optical coherence tomography (OCT) systems.

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Area of Science:

  • Biomedical Engineering
  • Optical Engineering
  • Materials Science

Background:

  • Compact size and high imaging speed are crucial for clinical optical coherence tomography (OCT) systems.
  • Microelectromechanical system (MEMS) scanning mirrors are vital for miniaturized OCT, but conventional fabrication is complex and costly, hindering clinical adoption.

Purpose of the Study:

  • To develop a cost-effective and simple-to-fabricate MEMS scanning mirror for miniaturized OCT systems.
  • To evaluate the performance of a novel two-axis polydimethylsiloxane-based MEMS (2A-PDMS-MEMS) scanning mirror.

Main Methods:

  • Fabrication of a two-axis polydimethylsiloxane-based MEMS (2A-PDMS-MEMS) scanning mirror using simple, low-cost processes.
  • Characterization of the 2A-PDMS-MEMS scanning mirror's performance, including AC/DC responses, scanning angles, field of view, and resonance frequencies.
  • Integration of the 2A-PDMS-MEMS scanning mirror into a swept-source OCT (SD-OCT) system.

Main Results:

  • The developed 2A-PDMS-MEMS scanning mirror has a compact size (15×15×15 mm³), wide scanning range (±16.6° X-axis, ±11.6° Y-axis), and fast response at low voltage.
  • Achieved a field of view of 29.8 mm × 20.5 mm with a 50 mm optical focal length and resonance frequencies of 82 Hz (X-axis) and 57 Hz (Y-axis).
  • Successfully acquired in vivo B-scan and volumetric OCT images of human fingertips and palms.

Conclusions:

  • The novel 2A-PDMS-MEMS scanning mirror offers a viable, low-cost solution for miniaturized OCT systems.
  • The developed MEMS mirror facilitates faster clinical translation and commercialization of OCT technology.
  • This advancement holds potential for broader applications in biomedical imaging and diagnostics.