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Incidence and characterization of canine rheumatoid factor
R E Halliwell1, L L Werner, D E Baum
1Department of Medical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610.
Veterinary Immunology and Immunopathology
|June 1, 1989
Abstract:
Rheumatoid factor (RF) was found in titers greater than 1:8 in 72.2% of cases of classical or definite canine rheumatoid arthritis (RA) and in 5.9% or normal sera. Serum fractionation and immunoabsorbant studies that much of the RF present was IgG, although activity was demonstrated in all 3 major immunoglobulin classes. Evidence of involvement of both IgG and IgM to form complexes of varying sizes was obtained.