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Updated: Mar 13, 2026
Author Spotlight: Efficient Detection of Immune Cell-Infiltration in Cancer Tissues Using Fluorescent Immunohistochemistry
Published on: January 26, 2024
CCN Detection of Cancer Tissues by Immunohistochemistry Staining
Cheng-Chi Chang1,2, Yue-Ju Li2,3, Min-Liang Kuo4
1Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan.
Abstract:
CCN family members are involved in many physiologic and pathological functions, and be detected in many different cancer types. Immunohistochemistry (IHC) is an important diagnostic pathology tool to demonstrate protein expression in clinical and research fields. Here, we explain the preparation of sample slides, staining procedure, and the problems that might be met during the time. The differential staining of CCN proteins is shown in breast cancer, oral cancer, lung cancer, colorectal cancer, and gastric cancer.
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