[Endocrine localization of Hodgkin's disease]

Among 130 patients with Hodgkin's disease hospitalized for a 13 year period were established two cases of primary extranodular localization in the thyroid gland and an extremely rare case of affection of the neurohypophysis as a manifestation of hematogenous dissemination. The clinical manifestations, therapeutic approach and the effect of the endocrine localization on the survival of the patients are presented. The prognosis was comparatively good in the patients with thyroid localization but in the patients with hypophyseal localization it was unfavourable. The diagnostic and therapeutic possibilities in Hodgkin's disease with endocrine localization are discussed.