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Updated: Jul 11, 2026

Electrophysiological Assessment of Murine Atria with High-Resolution Optical Mapping
Published on: February 22, 2018
[Complex assessment of the electrophysiologic changes in patients with left-ventricular cardiac overload]
Abstract:
130 healthy persons and 146 cardiac patients with left ventricular cardiac overload were examined by 4 electrophysiologic methods: corrected orthogonal electrocardiogram according to Frank, corrected orthogonal vectorcardiogram, space electrocardiogram, high-speed space electrocardiogram. 76 indices were examined. The cardiac patients were classified into two basic groups: patients with systolic overload and patients with diastolic overload. By variational analysis, performed in all patients, statistically significant differences were found between the cardiac patients and the healthy persons. On the basis of the criteria sensitivity, specificity and assessment of realization the best indices for every method were determined. In order to improve the sensitivity "sets" with sensitivity of 91-96% are established by mathematical calculations. The "sets" are made up of 4 indices from different methods and are suitable for inclusion in computer programs.
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