[Effect of autonomic pathology in uremia on the blood pressure during hemodialysis]

The state of the vegetative nervous system was studied by the deep respiration test, Valsalva test and the orthostatic test in 12 patients with terminal chronic renal failure and hypotension in the course of hemodialysis, 12 patients with stable hemodynamics in the course of hemodialysis and 12 healthy controls. By the deep respiration test the mean change of the cardiac rate in the patients with hypotension is significantly lower than that in the healthy controls (p less than 0.001) and that of the normotonic patients on hemodialysis (p less than 0.01). In the dialyzed normotonic patients the change of the cardiac rate is significantly lower than that in the healthy controls (p less than 0.02). Similar results are achieved with the Valsalva test. The impairment of the vegetative nervous system is considerably better expressed in the hypotensive patients. The proposed tests are noninvasive, easy to perform and give reliable information for the affection of the vegetative nervous system.