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Related Experiment Video

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Detecting Anastasis In Vivo by CaspaseTracker Biosensor

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Published on: February 1, 2018

Why STAN might not be dead.

Serena Xodo¹, Gabriele Saccone², Ewoud Schuit³

¹a Department of Gynecology and Obstetrics , School of Medicine, University of Udine , Udine , Italy.

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

|October 14, 2016

Summary

This summary is machine-generated.

A meta-analysis found ST analysis (STAN) did not improve perinatal outcomes for laboring women. Further research is needed to determine STAN

Keywords:

Cardiotocography STAN delivery labor nonstress test

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Area of Science:

Obstetrics and Gynecology
Fetal Monitoring
Clinical Trials

Background:

Intrapartum fetal heart rate monitoring is crucial for assessing fetal well-being during labor.
ST analysis (STAN) is an adjunct technology to conventional monitoring.
Previous randomized clinical trials (RCTs) have evaluated STAN's efficacy.

Purpose of the Study:

To summarize level-1 data from RCTs on STAN's use during labor.
To evaluate STAN's impact on perinatal outcomes and cesarean delivery rates.
To identify limitations and suggest future research directions for STAN.

Main Methods:

Meta-analysis of six high-quality RCTs.
Inclusion of data from 26,526 laboring singleton vertex births at term.
Analysis of STAN as an adjunct to conventional intrapartum fetal heart rate monitoring.

Main Results:

STAN did not improve perinatal outcomes.
STAN did not decrease cesarean delivery rates.
Significant heterogeneity was observed between low- and high-risk subgroups, suggesting STAN's effect may differ.

Conclusions:

Current level-1 data indicate no overall perinatal benefit of adding STAN to conventional monitoring.
Methodological differences in trials and lack of statistical power for subgroup analyses limit definitive conclusions.
Further research is warranted to explore STAN's potential value in specific populations or with refined methodologies.