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Updated: Mar 13, 2026

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection
Published on: December 15, 2023
[Tracing patients with chronic viral hepatitis]
A G Spruijt1, K R Wilting, G D Mithoe
1GGD Groningen, afd. Medische Milieukunde en Infectieziektebestrijding.
Objective:
To investigate the effect of an intervention in which medical-microbiological laboratories alert general practitioners (GPs) in writing about patients with a chronic hepatitis B or C infection in their practice, urging them to bring these patients under medical surveillance again now that treatment options have improved and guidelines have been revised.
Design:
Descriptive, prospective.
Method:
All patients who had been diagnosed with hepatitis B or C between 2003 and 2013 on the request of the GP, and for whom diagnostics by an internist, infectious diseases specialist or gastrointestinal/liver specialist had never been requested, were included. The requesting GP received a letter advising them to confirm the diagnosis, and if results were positive to refer the patient to a hepatitis centre. If the GP did not respond, or the healthcare practitioner involved was not the current GP, a written reminder was sent.
Results:
A total of 515 letters were sent initially; the final response following reminders was 362 (70%). Of these 362 patients, 69 (19%) still had an indication for referral and 45 (64%) were referred to a hepatitis centre.
Conclusion:
The intervention was successful, feasible and relatively simple.
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