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Updated: Mar 13, 2026

Intraoperative Ultrasound in Spinal Surgery
Published on: August 17, 2022
[Warfarin-associated epidural hematoma with spinal cord compression].
V A Byvaltsev1, A E Budaev2, V A Sorokovikov3
1Irkutsk Scientific Centre of Surgery and Traumatology, Irkutsk, Russia; Irkutsk Rail Road Hospital, Irkutsk, Russia.
Warfarin use can lead to dangerous central nervous system hemorrhages. This report details a rare case of spontaneous spinal epidural hematoma (SEH) linked to warfarin, emphasizing diagnosis and treatment.
Area of Science:
- Neurology
- Hematology
- Pharmacology
Background:
- Warfarin is a common anticoagulant with known risks.
- Hemorrhages in the central nervous system are severe warfarin-associated complications.
- Spontaneous spinal epidural hematomas (SEH) are rare, especially with warfarin use.
Observation:
- The authors report the first domestic case of spontaneous SEH associated with warfarin.
- This case highlights the diagnostic and therapeutic challenges of warfarin-associated SEH.
- A review of existing literature on warfarin and SEH is included.
Findings:
- Warfarin-associated spontaneous SEH is a critical but underreported complication.
- Timely diagnosis and appropriate treatment are crucial for managing SEH.
- This case contributes to understanding the clinical spectrum of warfarin-induced bleeding.
Implications:
- Increased awareness of warfarin-associated SEH is needed among clinicians.
- Further research into the mechanisms and management of SEH is warranted.
- This case report serves as a valuable reference for managing similar rare complications.
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